Radiation Dose Estimates for Tc-99m Teboroxime

	Estimated Radiation Dose (mGy/MBq)
ORGAN	mGy/MBq	rad/mCi
Adrenals	5.0E-03	1.8E-02
Brain	3.1E-03	1.1E-02
Breasts	2.1E-03	7.6E-03
Gallbladder Wall	3.4E-02	1.3E-01
LLI Wall	2.5E-02	9.3E-02
Small Intestine	1.9E-02	7.1E-02
Stomach	4.7E-03	1.7E-02
ULI Wall	3.6E-02	1.3E-01
Heart Wall	2.2E-02	8.0E-02
Kidneys	4.6E-03	1.7E-02
Liver	1.7E-02	6.2E-02
Lungs	7.6E-03	2.8E-02
Muscle	2.9E-03	1.1E-02
Ovaries	9.3E-03	3.5E-02
Pancreas	5.6E-03	2.1E-02
Red Marrow	3.6E-03	1.3E-02
Bone Surfaces	4.9E-03	1.8E-02
Skin	1.5E-03	5.6E-03
Spleen	3.2E-03	1.2E-02
Testes	1.9E-03	7.2E-03
Thymus	3.2E-03	1.2E-02
Thyroid	1.8E-03	6.6E-03
Urinary Bladder Wall	1.1E-02	3.9E-02
Uterus	7.1E-03	2.6E-02
Effective Dose Equivalent	1.2E-02 mSv/MBq	4.6E-02 rem/mCi

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Based on data gathered in human subjects by Narra et al., J Nucl Med 33:88-93, 1992. Assumed distribution and retention:

Brain 2.03% Tb = 173 hr
Liver 27.8% Tb = 6.0 hr
Lungs 13.2% Tb = 0.073 hr 8.02% Tb = 6.2 hr
Heart Wall 1.19% Tb = 3.7 hr 2.05% Tb = 0.088 hr
Gallbladder: receives 1/3 of activity leaving the liver, voids every 6 hours. 26.07% to small intestines, follows GI tract kinetics as in ICRP 30. 71.56% to urinary bladder, Tb = 47.8 hr. Dynamic bladder model with 4.8-hour voiding interval. Estimate calculated using phantom of Cristy & Eckerman (Report ORNL/TM-8381/V1 & V7)