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Radiation Dose Estimates for Tc-99m DMSA


  Estimated Radiation Dose
ORGAN mGy/MBq rad/mCi
     
Adrenals 1.2E-02 4.3E-02
Brain 1.3E-03 4.9E-03
Breasts 1.4E-03 5.0E-03
Gallbladder Wall 7.5E-03 2.8E-02
LLI Wall 3.3E-03 1.2E-02
Small Intestine 5.0E-03 1.9E-02
Stomach 5.2E-03 1.9E-02
ULI Wall 4.9E-03 1.8E-02
Heart Wall 2.9E-03 1.1E-02
Kidneys 1.9E-01 7.0E-01
Liver 5.7E-03 2.1E-02
Lungs 2.4E-03 9.0E-03
Muscle 2.9E-03 1.1E-02
Ovaries 3.5E-03 1.3E-02
Pancreas 8.7E-03 3.2E-02
Red Marrow 4.1E-03 1.5E-02
Bone Surfaces 5.0E-03 1.9E-02
Skin 1.6E-03 5.8E-03
Spleen 1.1E-02 4.0E-02
Testes 1.8E-03 6.8E-03
Thymus 1.8E-03 6.6E-03
Thyroid 1.6E-03 6.0E-03
Urinary Bladder Wall 1.5E-02 5.4E-02
Uterus 4.2E-03 1.6E-02
     
Effective Dose Equivalent 1.6E-02 mSv/MBq 6.0E-02 rem/mCi

Based on data gathered in human subjects by Arnold et al., J Nucl Med 16:357-367, 1975. Assumed distribution and retention:

Total body 80% Tb = 72 hr 20% Tb = 1.6 hr
Kidneys 44% Tb = ñ
Urinary bladder receives whole body clearance: 44.8%, Tb = 72 hr, 11.2%,

Tb = 1.6 hr. Bladder voiding interval 4.8 hours.

Estimate calculated using phantom of Cristy & Eckerman (Report ORNL/TM-8381/V1 & V7)