Radiation Dose Estimates for Tc-99m for the Adult for Disofenin, Lidofenin and Mebrofenin

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	Estimated Radiation Dose
ORGAN	mGy/MBq	rad/mCi
Adrenals	3.6E-03	1.3E-02
Brain	6.9E-05	2.6E-04
Breasts	4.7E-04	1.7E-03
Gallbladder Wall	1.1E-01	4.0E-01
LLI Wall	6.0E-02	2.2E-01
Small Intestine	4.4E-02	1.6E-01
Stomach	5.6E-03	2.1E-02
ULI Wall	8.6E-02	3.2E-01
Heart Wall	1.4E-03	5.4E-03
Kidneys	6.0E-03	2.2E-02
Liver	1.4E-02	5.2E-02
Lungs	1.1E-03	4.2E-03
Muscle	3.0E-03	1.1E-02
Ovaries	1.9E-02	7.1E-02
Pancreas	5.6E-03	2.1E-02
Red Marrow	3.9E-03	1.5E-02
Bone Surfaces	3.8E-03	1.4E-02
Skin	9.2E-04	3.4E-03
Spleen	2.5E-03	9.3E-03
Testes	1.7E-03	6.3E-03
Thymus	3.7E-04	1.4E-03
Thyroid	1.2E-04	4.5E-04
Urinary Bladder Wall	2.7E-02	9.9E-02
Uterus	1.4E-02	5.1E-02
Effective Dose Equivalent	2.5E-02 mSv/MBq	9.3E-02 rem/mCi

Biological model based on ICRP 53 (data gathered in human subjects).

Kidneys * = 0.012 hour Gallbladder contents * = 0.77 hour
Liver * = 0.80 hour Small Intestine * = 1.79 hour
Upper Large Intestine * = 2.34 hour Lower Large Intestine * = 1.14 hour
Urinary bladder * = 0.53 hour Remainder of body * = 0.14 hour

Dynamic bladder model with 4.8-hour voiding interval

Estimate calculated using phantom of Cristy & Eckerman (Report ORNL/TM-8381/V1 & V7)