Radiation Dose Estimates for In-111 Red Blood Cells

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	Estimated Radiation Dose (mGy/MBq)
ORGAN	mGy/MBq	rad/mCi
Adrenals	1.9E-01	7.0E-01
Brain	1.3E-01	4.7E-01
Breasts	1.1E-01	4.0E-01
Gallbladder Wall	1.9E-01	7.0E-01
LLI Wall	1.8E-01	6.7E-01
Small Intestine	1.9E-01	6.9E-01
Stomach	1.9E-01	6.9E-01
ULI Wall	1.8E-01	6.7E-01
Heart Wall	1.7E-01	6.3E-01
Kidneys	1.8E-01	6.7E-01
Liver	1.7E-01	6.5E-01
Lungs	1.5E-01	5.6E-01
Muscle	1.4E-01	5.2E-01
Ovaries	1.9E-01	7.0E-01
Pancreas	2.2E-01	8.3E-01
Red Marrow	1.5E-01	5.4E-01
Bone Surfaces	2.2E-01	8.3E-01
Skin	9.6E-02	3.5E-01
Spleen	7.6E-01	2.8E+00
Testes	1.4E-01	5.0E-01
Thymus	1.5E-01	5.6E-01
Thyroid	1.5E-01	5.6E-01
Urinary Bladder Wall	1.7E-01	6.5E-01
Uterus	1.9E-01	7.0E-01
Effective Dose Equivalent	2.0E-01 mSv/MBq	7.5E-01 rem/mCi

Based on model in humans for Cr-51 RBC's by Powsner and Raeside, Diagnostic Nuclear Medicine, 1971, p. 184. Assumed distribution and retention:

100% to blood, Tb = 35 days
Of material removed from blood:
Liver 40% Tb = 50 days
Spleen 40% Tb = 50 days
Marrow 20% Tb = 50 days
Clearance through urinary bladder. Bladder voiding interval 4.8 hours.

Estimate calculated using phantom of Cristy & Eckerman (Report ORNL/TM-8381/V1 & V7). Bone and marrow model of Eckerman (Aspects of dosimetry of radionuclides within the skeleton with particular emphasis on the active marrow, In Fourth International Radiopharmaceutical Dosimetry Symposium; A.T. Schlafke-Stelson and E. E. Watson eds. CONF-851113, Oak Ridge Associated Universities, Oak Ridge, TN 37831, 1986. pp 514-534.) used.