Radiation Dose Estimates for I-131 mIBG (i.v. injection)

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	Estimated Radiation Dose (mGy/MBq)
ORGAN	mGy/MBq	rad/mCi
Adrenals	2.1E-01	7.6E-01
Brain	4.7E-02	1.7E-01
Breasts	5.4E-02	2.0E-01
Gallbladder Wall	1.4E-01	5.2E-01
LLI Wall	7.2E-02	2.7E-01
Small Intestine	7.5E-02	2.8E-01
Stomach	7.8E-02	2.9E-01
ULI Wall	7.9E-02	2.9E-01
Heart Wall	3.8E-01	1.4E+00
Kidneys	8.8E-02	3.3E-01
Liver	7.8E-01	2.9E+00
Lungs	7.4E-02	2.7E-01
Muscle	6.2E-02	2.3E-01
Ovaries	7.4E-02	2.7E-01
Pancreas	1.1E-01	3.9E-01
Red Marrow	7.4E-02	2.7E-01
Bone Surfaces	6.5E-02	2.4E-01
Skin	2.4E-01	8.8E-01
Spleen	4.8E-02	1.8E-01
Testes	5.8E-01	2.2E+00
Thymus	5.8E-02	2.2E-01
Thyroid	6.4E-02	2.4E-01
Urinary Bladder Wall	9.0E-02	3.3E-01
Uterus	7.6E-01	2.8E+00
	8.90E-02	3.30E-01
Effective Dose Equivalent	2.1E-01 mSv/MBq	7.8E-01 rem/mCi

Based on data gathered in patients - Jacobsson et al, 4th International Radiopharmaceutical Dosimetry Symposium, CONF-851113, pp. 389-398. Assumed distribution and retention:
Total body 63 % Tb = 32.8 hours 36 % Tb = 3.05 hours 1 % Tb = ñ
Liver 21 % Tb = 32.8 hours 15 % Tb = 3.05 hours 0.3 % Tb = ñ
Spleen 0.6 % Tb = 178 hours

Estimate calculated using phantom of Cristy & Eckerman (Report ORNL/TM-8381/V1 & V7)