Back

Radiation Dose Estimates for I-131 Hippuran


  Estimated Radiation Dose (mGy/MBq)
ORGAN mGy/MBq rad/mCi
     
Adrenals 2.1E-03 7.7E-03
Brain 5.5E-04 2.1E-03
Breasts 6.7E-04 2.5E-03
Gallbladder Wall 3.0E-03 1.1E-02
LLI Wall 2.6E-02 9.5E-02
Small Intestine 1.0E-02 3.8E-02
Stomach 2.1E-03 7.7E-03
ULI Wall 8.0E-03 2.9E-02
Heart Wall 9.0E-04 3.3E-03
Kidneys 4.5E-02 1.7E-01
Liver 1.7E-03 6.4E-03
Lungs 7.7E-04 2.8E-03
Muscle 6.7E-03 2.5E-02
Ovaries 2.3E-02 8.6E-02
Pancreas 2.1E-03 7.7E-03
Red Marrow 4.8E-03 1.8E-02
Bone Surfaces 3.6E-03 1.3E-02
Skin 2.6E-03 9.6E-03
Spleen 2.0E-03 7.5E-03
Testes 1.7E-02 6.4E-02
Thymus 7.3E-04 2.7E-03
Thyroid 6.4E-04 2.4E-03
Urinary Bladder Wall 1.4E+00 5.3E+00
Uterus 5.4E-02 2.0E-01
     
Effective Dose Equivalent 1.0E-01 mSv/MBq 3.7E-01 rem/mCi

Based on data gathered in patients by Lindmo et al. (Med Phys 1(4):193-197, 1974). Assumed distribution and retention:

Total body 49% Tb = 0.285 hr 51% Tb = 0.0392 hr
Kidney Residence time = 6.2 minutes
All activity cleared through urinary bladder. Bladder voiding interval 4.8 hours.
Estimate calculated using phantom of Cristy & Eckerman (Report ORNL/TM-8381/V1 & V7)