Radiation Dose Estimates for I-125 mIBG

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	Estimated Radiation Dose (mGy/MBq)
ORGAN	mGy/MBq	rad/mCi
Adrenals	4.2E-02	1.6E-01
Brain	1.4E-02	5.3E-02
Breasts	1.2E-02	4.5E-02
Gallbladder Wall	4.3E-02	1.6E-01
LLI Wall	1.7E-02	6.1E-02
Small Intestine	1.6E-02	5.9E-02
Stomach	1.7E-02	6.4E-02
ULI Wall	1.7E-02	6.2E-02
Heart Wall	8.3E-02	3.1E-01
Kidneys	2.0E-02	7.4E-02
Liver	2.2E-01	8.2E-01
Lungs	2.3E-02	8.3E-02
Muscle	1.6E-02	5.8E-02
Ovaries	1.6E-02	5.9E-02
Pancreas	2.6E-02	9.6E-02
Red Marrow	1.2E-02	4.4E-02
Bone Surfaces	3.1E-02	1.2E-01
Salivary Glands	7.0E-02	2.6E-01
Skin	1.1E-02	3.9E-02
Spleen	1.6E-01	5.9E-01
Testes	1.3E-02	4.8E-02
Thymus	1.5E-02	5.7E-02
Thyroid	4.6E-02	1.7E-01
Urinary Bladder Wall	1.4E-01	5.1E-01
Uterus	2.00E-02	7.50E-02
Effective Dose Equivalent	5.1E-02 mSv/MBq	1.9E-01 rem/mCi

Based on data gathered in patients - Jacobsson et al, 4th International
Radiopharmaceutical Dosimetry Symposium, CONF-851113, pp. 389-398. Assumed distribution and retention:
Total body 63 % Tb = 32.8 hours 36 % Tb = 3.05 hours
1 % Tb = ñ
Liver 21 % Tb = 32.8 hours 15 % Tb = 3.05 hours
0.3 % Tb = ñ
Spleen 0.6 % Tb = 178 hours
Sal. glands 0.04 % Tb = 32.8 hours
Thyroid 0.005 % Tb = 168 hours
Adrenals 0.02 % Tb = 48.6 hours
Heart wall 0.8 % Tb = 120 hours

Dynamic Bladder Model used (4.80 hour void)
36 % Tb = 3.00 hours 63 % Tb = 33.6 hours
Dose to salivary glands is self-dose only, based on 77 g mass and photon absorbed
fractions from MIRD Pamphlet No. 8. Salivary gland activity did not contribute to other organ doses. Estimate calculated using phantom of Cristy & Eckerman (Report ORNL/TM-8381/V1 & V7)