Radiation Dose Estimates for I-123 Hippuran

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	Estimated Radiation Dose (mGy/MBq)
ORGAN	mGy/MBq	rad/mCi
Adrenals	7.7E-04	2.8E-03
Brain	1.7E-04	6.1E-04
Breasts	1.7E-04	6.4E-04
Gallbladder Wall	1.0E-03	3.8E-03
LLI Wall	1.1E-02	4.2E-02
Small Intestine	4.1E-03	1.5E-02
Stomach	7.0E-04	2.6E-03
ULI Wall	3.1E-03	1.1E-02
Heart Wall	2.8E-04	1.0E-03
Kidneys	9.9E-03	3.7E-02
Liver	5.6E-04	2.1E-03
Lungs	2.4E-04	8.8E-04
Muscle	2.8E-03	1.1E-02
Ovaries	1.0E-02	3.7E-02
Pancreas	7.2E-04	2.6E-03
Red Marrow	1.7E-03	6.1E-03
Bone Surfaces	2.0E-03	7.4E-03
Skin	9.0E-04	3.3E-03
Spleen	7.3E-04	2.7E-03
Testes	7.0E-03	2.6E-02
Thymus	2.1E-04	7.8E-04
Thyroid	1.9E-04	7.1E-04
Urinary Bladder Wall	3.0E-01	1.1E+00
Uterus	2.6E-02	9.5E-02
Effective Dose Equivalent	2.4E-02 mSv/MBq	8.8E-02 rem/mCi

Based on data gathered in patients by Lindmo et al. (Med Phys 1(4):193-197, 1974). Assumed distribution and retention:

Total body 49% Tb = 0.285 hr 51% Tb = 0.0392 hr
Kidney Residence time = 6.2 minutes
All activity cleared through urinary bladder. Dynamic bladder model with 4.8-hour voiding interval
Estimate calculated using phantom of Cristy & Eckerman (Report ORNL/TM-8381/V1 & V7)