Radiation Dose Estimates for Co-58 Vitamin B-12 (Cyanocobalamin)

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	Estimated Radiation Dose (mGy/MBq)
	No Flushing Dose		With Flushing Dose
ORGAN	Normals	Pernicious Anemia	Normals	Pernicious Anemia
Adrenals	1.1E+01	1.4E+00	7.3E+00	9.9E-01
Brain	1.3E+00	1.6E-01	8.3E-01	1.0E-01
Breasts	2.9E+00	3.8E-01	1.9E+00	2.5E-01
Gallbladder Wall	2.0E+01	2.7E+00	1.3E+01	1.9E+00
LLI Wall	3.3E+00	4.0E+00	2.6E+00	3.9E+00
Small Intestine	4.5E+00	1.4E+00	3.1E+00	1.2E+00
Stomach	4.9E+00	9.0E-01	3.3E+00	7.1E-01
ULI Wall	6.2E+00	2.5E+00	4.3E+00	2.2E+00
Heart Wall	6.6E+00	8.6E-01	4.4E+00	5.8E-01
Kidneys	7.8E+00	1.1E+00	5.3E+00	8.0E-01
Liver	5.3E+01	6.8E+00	3.5E+01	4.7E+00
Lungs	5.6E+00	7.2E-01	3.7E+00	4.9E-01
Muscle	3.1E+00	5.0E-01	2.1E+00	3.7E-01
Ovaries	3.1E+00	1.3E+00	2.2E+00	1.2E+00
Pancreas	9.3E+00	1.3E+00	6.2E+00	9.0E-01
Red Marrow	3.7E+00	6.4E-01	2.5E+00	4.8E-01
Bone Surfaces	3.0E+00	4.6E-01	2.0E+00	3.3E-01
Skin	2.0E+00	3.0E-01	1.4E+00	2.1E-01
Spleen	3.3E+00	5.1E-01	2.2E+00	3.7E-01
Testes	1.5E+00	2.9E-01	1.0E+00	2.2E-01
Thymus	3.0E+00	3.9E-01	2.0E+00	2.6E-01
Thyroid	1.8E+00	2.3E-01	1.2E+00	1.5E-01
Urinary Bladder Wall	2.3E+00	5.7E-01	1.6E+00	4.8E-01
Uterus	2.8E+00	7.6E-01	1.9E+00	6.4E-01
Effective Dose Equivalent	8.5E+00	1.6E+00	5.7E+00	1.3E+00

* Based on model in ICRP 53.
Dynamic bladder model with 4.8-hour voiding interval
Estimate calculated using phantom of Cristy & Eckerman (Report ORNL/TM-8381/V1 & V7)